Perinatal & Placental Pathology
Other Sub-Specialists
Primary Contact
François M. Cady, M.D.
Dr. Cady attended medical school at the Louisiana State University Health Sciences Center in Shreveport. He is board certified in Hematopathology, Anatomic Pathology, and Clinical Pathology.
Full BioWhy CellNetix?
- The extraordinary level of expertise (three fellowship trained Placental & Perinatal pathologists) coupled with high specimen volume results in superb patient care.
- Our Perinatal and Placental Pathologists are available to provide their expertise for questions, evaluations and second opinions on all cases pertaining to their specialty.
- Our state-of-the-art bar-coding system has been shown to reduce common histologic slide identification errors by 95% and overall case identification errors by 62%.
- State-of-the-art Information Technology systems with EMR interface capabilities
- Full service billing department for direct billing of patient insurance, as well as payment plans for cash-paying patients
- Custom test requisitions upon request
- 94% of our biopsy results are returned within 48 hours
- 24/7 priority access to your local pathologists
Publications
Langston C, Kaplan C, Macpherson T, Manci E, Peevy K, Clark B, Murtagh C, Cox S, Glenn G. Practice guideline for examination of the placenta: developed by the Placental Pathology Practice Guideline Development Task Force of the College of American Pathologists. Arch Pathol Lab Med. 1997 May;121(5):449-76. Katzman PJ, Genest DR. Maternal floor infarction and massive perivillous fibrin deposition: histological definitions, association with intrauterine fetal growth restriction, and risk of recurrence. Pediatr Dev Pathol. 2002 Mar-Apr;5(2):159-64. Redline RW. Severe fetal placental vascular lesions in term infants with neurologic impairment. Am J Obstet Gynecol. 2005 Feb;192(2):452-7. Redline RW, Patterson P. Villitis of unknown etiology is associated with major infiltration of fetal tissue by maternal inflammatory cells. Am J Pathol. 1993 Aug;143(2):332-6. Redline RW, Ariel I, Baergen RN, Desa DJ, Kraus FT, Roberts DJ, Sander CM. Fetal vascular obstructive lesions: nosology and reproducibility of placental reaction patterns. Pediatr Dev Pathol. 2004 Sep-Oct;7(5):443-52. Epub 2004 Jul 30. Evers IM, Nikkels PG, Sikkema JM, Visser GH. Placental pathology in women with type 1 diabetes and in a control group with normal and large-for-gestational-age infants. Placenta. 2003 Sep-Oct;24(8-9):819-25. Krakowiak P, Smith EN, de Bruyn G, Lydon-Rochelle MT. Risk factors and outcomes associated with a short umbilical cord. Obstet Gynecol. 2004 Jan;103(1):119-27.
The placenta serves as the physiologic bridge linking the maternal and fetal vasculature. The gross and microscopic examination of placental tissues can provide insight into a variety of maternal and fetal disorders. Placental pathology can identify maternal and fetal infection, perfusion abnormalities, features of maternal thrombophilia, and rarely, benign or malignant tumors. Some abnormalities, such as maternal floor infarct, massive perivillous fibrin deposition, and villitis of unknown etiology may affect subsequent pregnancies. Accurate identification of these lesions may affect future obstetric counseling and management.
Placental examination is particularly important in the setting of a stillborn infant. Pathologic examination can document, when present, the type, extent, and timing of placental injury as it relates to the cause of death. This type of consultation can provide a great deal of information to the medical team and grieving families. The results derived from placental examination provide answers and can serve to enhance communication between medical providers and families, which may mitigate medicolegal claims.
CellNetix pathologists examine approximately 3600 placenta and perinatal specimens each year under the direction of three fellowship trained Placental & Perinatal pathologists. Our Placental and Perinatal Pathology working group is led by Francois M. Cady, M.D. who is board certified in Anatomic Pathology, Clinical Pathology, Hematopathology, and holds additional fellowship training in Placental and Perinatal Pathology as well as Surgical Pathology.
Our Strengths
- The extraordinary level of expertise (three fellowship trained Placental & Perinatal pathologists) coupled with high specimen volume results in superb patient care.
- Our Perinatal and Placental Pathologists are available to provide their expertise for questions, evaluations and second opinions on all cases pertaining to their specialty.
- Our state-of-the-art bar-coding system has been shown to reduce common histologic slide identification errors by 95% and overall case identification errors by 62%.
- 94% of our biopsy results are returned within 48 hours
- 24/7 priority access to your local pathologists
- Reports convey information clearly, concisely and correctly
- State-of-the-art Information Technology systems with EMR interface capabilities
- Full service billing department for direct billing of patient insurance, as well as payment plans for cash-paying patients
- Custom test requisitions upon request
Types of Testing We Do
- Placenta and Fetal gross and microscopic examination.
Types of Conditions and Diseases encountered:
- Ascending amniotic fluid infection/chorioamnionitis.
- Infection/TORCH
- Placental insufficiency.
- Congenital anomaly.
- Placentation of multiple gestation.
- Trophoblastic disease (complete hydatidiform mole, partial hydatidiform mole, choriocarcinoma, placental site trophoblastic tumor).
- Vascular abnormalities.
- Disorders of fetal vascular development, including chorangiosis.
- Circulatory problems.
- Abortion/miscarriage.
- Gestational diabetes mellitus.
- Placental abruption.