LMO2

  • Tech Only CPT
  • Tech Pro CPT
  • PowerPath Code
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Disease State Diffuse Large B Cell Lymphoma
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

This is a send out test.

Diagnostic Utility

Identifies: A cysteine-rich protein that also plays a central and crucial role in hematopoietic development. In the setting of diffuse large B-cell lymphomas (DLBCLs), LMO2 has high sensitivity in differentiating between germinal center B-cell (GCB) DLBCLs and non-GCB DLBCLs. Based on the recently published Tally Method algorithm, LMO2 will be used in a panel, along with CD10, GCET1, MUM1, and FoxP1, to help distinguish between GCB versus non-GCB origin among DLBCLs. Subcellular Localization: Nuclear